Property prediction · Sequence analysis

TLimmuno2

(Work in Progress)

Score how likely a peptide-MHC class II pair is to provoke a CD4 T-cell response.

Runs TLimmuno2, an LSTM model transferred from class II binding affinity data onto immunogenicity, over peptides paired with an MHC class II allele. Useful for anti-drug-response risk on a biologic as well as for vaccine epitope selection.

Documentation ↗ Home page ↗ Paper ↗ Source code ↗

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Peptide 13 to 21 residues, the range the class II model was trained on.

MHC class II allele

Peptide and allele pairs One pair per line, as peptide,allele.

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